Publications

Featured publications

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

July 28, 2025 | Journal of the American Society for Mass Spectrometry

Arnik Shah, et al.

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

Arnik Shah, Parth Shah, Alex Johnson, Jean Bender, Dmitry Gumerov, Jingwen Ding, Scott Mack, Matthew D. Stone, Maggie A. Ostrowski

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A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

November 2, 2023 | The New England Journal of Medicine

Mohit Mathur, et al.

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

Mohit Mathur, Jonathan Barratt, Bobby Chacko, Tak Mao Chan, Laura Kooienga, Kook-Hwan Oh, Manisha Sahay, Yusuke Suzuki, Muh Geot Wong, Jill Yarbrough, Jing Xia, Brian J G Pereira

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Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

April 5, 2023 | Frontiers in Molecular Biosciences

Steven Pregizer, et al.

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Steven Pregizer, Thom Vreven, Mohit Mathur, Luke Robinson

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Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic.

April 23, 2013 | PLoS One

Karunya Srinivasan et al.

Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic.

Karunya Srinivasan, Rahul Raman, Akila Jayaraman, Karthik Viswanathan, Ram Sasisekharan

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Modular glycosphere assays for high-throughput functional characterization of influenza viruses.

April 15, 2013 | BMC Biotechnology

Sven N Hobbie et al.

Modular glycosphere assays for high-throughput functional characterization of influenza viruses.

Sven N Hobbie, Karthik Viswanathan, Ido Bachelet, Udayanath Aich, Zachary Shriver, Vidya Subramanian, Rahul Raman, Ram Sasisekharan

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Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency.

April 8, 2013 | Proceedings of the National Academy of Sciences of the United States of America

Kannan Tharakaraman et al.

Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency.

Kannan Tharakaraman, Luke N Robinson, Andrew Hatas, Yi-Ling Chen, Liu Siyue, S Raguram, V Sasisekharan, Gerald N Wogan, Ram Sasisekharan

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Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.

February 20, 2013 | PloS One

Karunya Srinivasan et al.

Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.

Karunya Srinivasan, Rahul Raman, Akila Jayaraman, Karthik Viswanathan, Ram Sasisekharan

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Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

December 19, 2011 | Scientific Reports

Venkataramanan Soundararajan et al.

Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

Venkataramanan Soundararajan, Shu Zheng, Neel Patel, Ken Warnock, Rahul Raman, Ian A Wilson, S Raguram, V Sasisekharan, Ram Sasisekharan

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Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay.

April 20, 2011 | The FEBS Journal

Udayanath Aich et al.

Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay.

Udayanath Aich, Nia Beckley, Zachary Shriver, Rahul Raman, Karthik Viswanathan, Sven Hobbie, Ram Sasisekharan

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A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets.

March 2, 2011 | PLoS One

Karthik Viswanathan et al.

A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets.

Karthik Viswanathan, Xiaoying Koh, Aarthi Chandrasekaran, Claudia Pappas, Rahul Raman, Aravind Srinivasan, Zachary Shriver, Terrence M Tumpey, Ram Sasisekharan

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Featured publications

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic.

Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic.

Modular glycosphere assays for high-throughput functional characterization of influenza viruses.

Modular glycosphere assays for high-throughput functional characterization of influenza viruses.

Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency.

Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency.

Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.

Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.

Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay.

Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay.

A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets.

A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets.

Determinants of glycan receptor specificity of H2N2 influenza A virus hemagglutinin.

Determinants of glycan receptor specificity of H2N2 influenza A virus hemagglutinin.

Glycans as receptors for influenza pathogenesis.

Glycans as receptors for influenza pathogenesis.

Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957.

Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957.