Publications - Visterra

Featured publications

Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study

March 7, 2020 | Antiviral Research

Susan E Sloan et al.

Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study

Susan E Sloan, Kristy J Szretter, Bharathi Sundaresh, Kristin M Narayan, Patrick F Smith, David Skurnik, Sylvain Bedard, José M Trevejo, David Oldach, Zachary Shriver

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Quantifying the nativeness of antibody sequences using long short-term memory networks

December 31, 2019 | Protein Engineering, Design, and Selection

Andrew M Wollacott et al.

Quantifying the nativeness of antibody sequences using long short-term memory networks

Andrew M Wollacott, Chonghua Xue, Qiuyuan Qin, June Hua, Tanggis Bohnuud, Karthik Viswanathan, Vijaya B Kolachalama

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A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

March 16, 2019 | Kidney International

James R Myette et al.

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

James R Myette, Toshiki Kano, Hitoshi Suzuki, Susan E Sloan, Kristy J Szretter, Boopathy Ramakrishnan, Hedy Adari, Ketan D Deotale, Frank Engler, Zachary Shriver, Andrew M Wollacott, Yusuke Suzuki, Brian J G Pereira

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Amino acid interaction networks provide a new lens for therapeutic antibody discovery and anti-viral drug optimization.

April 11, 2015 | Current Opinion in Virology

Karthik Viswanathan et al.

Amino acid interaction networks provide a new lens for therapeutic antibody discovery and anti-viral drug optimization.

Karthik Viswanathan, Zachary Shriver, Gregory J Babcock

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Structural determinants for naturally evolving H5N1 hemagglutinin to switch its receptor specificity.

June 20, 2013 | Cell

Kannan Tharakaraman et al.

Structural determinants for naturally evolving H5N1 hemagglutinin to switch its receptor specificity.

Kannan Tharakaraman, Rahul Raman, Karthik Viswanathan, Nathan W Stebbins, Akila Jayaraman, Arvind Krishnan, V Sasisekharan, Ram Sasisekharan

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Glycan receptor binding of the influenza A virus H7N9 hemagglutinin.

June 6, 2013 | Cell

Kannan Tharakaraman et al.

Glycan receptor binding of the influenza A virus H7N9 hemagglutinin.

Kannan Tharakaraman, Akila Jayaraman, Rahul Raman, Karthik Viswanathan, Nathan W Stebbins, David Johnson, Zachary Shriver, V Sasisekharan, Ram Sasisekharan

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Recognition of heparan sulfate by clinical strains of dengue virus serotype 1 using recombinant subviral particles.

May 22, 2013 | Virus Research

Charlermchai Artpradit et al.

Recognition of heparan sulfate by clinical strains of dengue virus serotype 1 using recombinant subviral particles.

Charlermchai Artpradit, Luke N Robinson, Boris K Gavrilov, Troy T Rurak, Mathuros Ruchirawat, Ram Sasisekharan

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Quantitative characterization of glycan-receptor binding of H9N2 influenza A virus hemagglutinin.

April 23, 2013 | PLoS One

Karunya Srinivasan et al.

Quantitative characterization of glycan-receptor binding of H9N2 influenza A virus hemagglutinin.

Karunya Srinivasan, Rahul Raman, Akila Jayaraman, Karthik Viswanathan, Ram Sasisekharan

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Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic.

April 23, 2013 | PLoS One

Karunya Srinivasan et al.

Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic.

Karunya Srinivasan, Rahul Raman, Akila Jayaraman, Karthik Viswanathan, Ram Sasisekharan

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Modular glycosphere assays for high-throughput functional characterization of influenza viruses.

April 15, 2013 | BMC Biotechnology

Sven N Hobbie et al.

Modular glycosphere assays for high-throughput functional characterization of influenza viruses.

Sven N Hobbie, Karthik Viswanathan, Ido Bachelet, Udayanath Aich, Zachary Shriver, Vidya Subramanian, Rahul Raman, Ram Sasisekharan

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Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency.

April 8, 2013 | Proceedings of the National Academy of Sciences of the United States of America

Kannan Tharakaraman et al.

Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency.

Kannan Tharakaraman, Luke N Robinson, Andrew Hatas, Yi-Ling Chen, Liu Siyue, S Raguram, V Sasisekharan, Gerald N Wogan, Ram Sasisekharan

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Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.

February 20, 2013 | PloS One

Karunya Srinivasan et al.

Quantitative description of glycan-receptor binding of influenza A virus H7 hemagglutinin.

Karunya Srinivasan, Rahul Raman, Akila Jayaraman, Karthik Viswanathan, Ram Sasisekharan

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Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

December 19, 2011 | Scientific Reports

Venkataramanan Soundararajan et al.

Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors.

Venkataramanan Soundararajan, Shu Zheng, Neel Patel, Ken Warnock, Rahul Raman, Ian A Wilson, S Raguram, V Sasisekharan, Ram Sasisekharan

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