Publications - Visterra

Featured publications

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

April 5, 2023 | Frontiers in Molecular Biosciences

Steven Pregizer, et. al.

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Steven Pregizer, Thom Vreven, Mohit Mathur, Luke Robinson

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Quantifying the nativeness of antibody sequences using long short-term memory networks

December 31, 2019 | Protein Engineering, Design, and Selection

Andrew M Wollacott et al.

Quantifying the nativeness of antibody sequences using long short-term memory networks

Andrew M Wollacott, Chonghua Xue, Qiuyuan Qin, June Hua, Tanggis Bohnuud, Karthik Viswanathan, Vijaya B Kolachalama

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A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

March 16, 2019 | Kidney International

James R Myette et al.

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

James R Myette, Toshiki Kano, Hitoshi Suzuki, Susan E Sloan, Kristy J Szretter, Boopathy Ramakrishnan, Hedy Adari, Ketan D Deotale, Frank Engler, Zachary Shriver, Andrew M Wollacott, Yusuke Suzuki, Brian J G Pereira

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Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

April 5, 2023 | Frontiers in Molecular Biosciences

Steven Pregizer, et. al.

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Steven Pregizer, Thom Vreven, Mohit Mathur, Luke Robinson

>READ

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers

May 10, 2022 | Kidney International Reports

Mohit Mathur,et. al

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers

Mohit Mathur, Jonathan Barratt, Yusuke Suzuki, Frank Engler, Marcela F. Pasetti, Jill Yarbrough, Susan Sloan, David Oldach

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Modeling cell-specific dynamics and regulation of the common gamma chain cytokines

April 27, 2021 | Cell Reports

Ali M. Farhat et al.

Modeling cell-specific dynamics and regulation of the common gamma chain cytokines

Ali M. Farhat, Adam C. Weiner, Cori Posner, Zoe S. Kim, Brian Orcutt-Jahns, Scott M. Carlson, Aaron S. Meyer

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Characterization of an Antibody Recognizing the Conserved Inner Core of Pseudomonas aeruginosa Lipopolysaccharides

November 3, 2020 | Biochemistry

Stefano Elli et al.

Characterization of an Antibody Recognizing the Conserved Inner Core of Pseudomonas aeruginosa Lipopolysaccharides

Stefano Elli, Anna Alekseeva, Boopathy Ramakrishnan, Tyree Koch, Andrew Wollacott, Karthik Viswanathan, Kai Li, James C Delaney, Zachary Shriver, Obadiah Plante, Marco Guerrini

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VIS832, a novel CD138-targeting monoclonal antibody, potently induces killing of human multiple myeloma and further synergizes with IMiDs or bortezomib in vitro and in vivo

November 2, 2020 | Blood Cancer Journal

Tengteng Yu et al.

VIS832, a novel CD138-targeting monoclonal antibody, potently induces killing of human multiple myeloma and further synergizes with IMiDs or bortezomib in vitro and in vivo

Tengteng Yu, Bharat Chaganty, Liang Lin, Lijie Xing, Boopathy Ramakrishnan, Kenneth Wen, Phillip A Hsieh, Andrew Wollacott, Karthik Viswanathan, Hedy Adari, Shih-Feng Cho, Yuyin Li, Hailin Chen, Wenjuan Yang, Yan Xu, Gang An, Lugui Qiu, Nikhil Munshi, Gregory Babcock, Zachary Shriver, James R Myette, Kenneth C Anderson, Yu-Tzu Tai

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Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study

March 7, 2020 | Antiviral Research

Susan E Sloan et al.

Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study

Susan E Sloan, Kristy J Szretter, Bharathi Sundaresh, Kristin M Narayan, Patrick F Smith, David Skurnik, Sylvain Bedard, José M Trevejo, David Oldach, Zachary Shriver

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Quantifying the nativeness of antibody sequences using long short-term memory networks

December 31, 2019 | Protein Engineering, Design, and Selection

Andrew M Wollacott et al.

Quantifying the nativeness of antibody sequences using long short-term memory networks

Andrew M Wollacott, Chonghua Xue, Qiuyuan Qin, June Hua, Tanggis Bohnuud, Karthik Viswanathan, Vijaya B Kolachalama

>READ

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

March 16, 2019 | Kidney International

James R Myette et al.

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

>READ

Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data

February 13, 2019 | Journal of Molecular Recognition

Andrew M Wollacott et al.

Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data

Andrew M Wollacott, Luke N Robinson, Boopathy Ramakrishnan, Hamid Tissire, Karthik Viswanathan, Zachary Shriver, Gregory J Babcock

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Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

January 9, 2019 | EBioMedicine

Ellie Hershberger et al.

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

Ellie Hershberger, Susan Sloan, Kristin Narayan, Catherine A Hay, Patrick Smith, Frank Engler, Rienk Jeeninga, Saskia Smits, Jose Trevejo, Zach Shriver, David Oldach

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