Publications

Featured publications

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

July 28, 2025 | Journal of the American Society for Mass Spectrometry

Arnik Shah, et al.

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

Arnik Shah, Parth Shah, Alex Johnson, Jean Bender, Dmitry Gumerov, Jingwen Ding, Scott Mack, Matthew D. Stone, Maggie A. Ostrowski

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A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

November 2, 2023 | The New England Journal of Medicine

Mohit Mathur, et al.

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

Mohit Mathur, Jonathan Barratt, Bobby Chacko, Tak Mao Chan, Laura Kooienga, Kook-Hwan Oh, Manisha Sahay, Yusuke Suzuki, Muh Geot Wong, Jill Yarbrough, Jing Xia, Brian J G Pereira

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Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

April 5, 2023 | Frontiers in Molecular Biosciences

Steven Pregizer, et al.

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Steven Pregizer, Thom Vreven, Mohit Mathur, Luke Robinson

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Quantifying the nativeness of antibody sequences using long short-term memory networks

December 31, 2019 | Protein Engineering, Design, and Selection

Andrew M Wollacott, et. al.

Quantifying the nativeness of antibody sequences using long short-term memory networks

Andrew M Wollacott, Chonghua Xue, Qiuyuan Qin, June Hua, Tanggis Bohnuud, Karthik Viswanathan, Vijaya B Kolachalama

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A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

March 16, 2019 | Kidney International

James R Myette et al.

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

James R Myette, Toshiki Kano, Hitoshi Suzuki, Susan E Sloan, Kristy J Szretter, Boopathy Ramakrishnan, Hedy Adari, Ketan D Deotale, Frank Engler, Zachary Shriver, Andrew M Wollacott, Yusuke Suzuki, Brian J G Pereira

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Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data

February 13, 2019 | Journal of Molecular Recognition

Andrew M Wollacott et al.

Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data

Andrew M Wollacott, Luke N Robinson, Boopathy Ramakrishnan, Hamid Tissire, Karthik Viswanathan, Zachary Shriver, Gregory J Babcock

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Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

January 9, 2019 | EBioMedicine

Ellie Hershberger et al.

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

Ellie Hershberger, Susan Sloan, Kristin Narayan, Catherine A Hay, Patrick Smith, Frank Engler, Rienk Jeeninga, Saskia Smits, Jose Trevejo, Zach Shriver, David Oldach

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A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

November 5, 2018 | Nature Chemistry

Daniel T Cohen et al.

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

Daniel T Cohen, Chi Zhang, Colin M Fadzen, Alexander J Mijalis, Liana Hie, Kenneth D Johnson, Zachary Shriver, Obadiah Plante, Scott J Miller, Stephen L Buchwald, Bradley L Pentelute

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Antibody-Bactericidal Macrocyclic Peptide Conjugates to Target Gram Negative Bacteria

September 14, 2018 | Chembiochem: A European Journal of Chemical Biology

Fayçal Touti et al.

Antibody-Bactericidal Macrocyclic Peptide Conjugates to Target Gram Negative Bacteria

Fayçal Touti, Guillaume Lautrette, Kenneth D Johnson, James C Delaney, Andrew Wollacott, Hamid Tissire, Karthik Viswanathan, Zachary Shriver, Surin K Mong, Alexander J Mijalis, Obadiah J Plante, Bradley L Pentelute

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Extending human IgG half-life using structure-guided design.

May 3, 2018 | mAbs

Brian J. Booth et al.

Extending human IgG half-life using structure-guided design.

Brian J. Booth, Boopathy Ramakrishnan, Kristin Narayan, Andrew M. Wollacott ,Gregory J. Babcock, Zachary Shriver & Karthik Viswanathan

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Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

February 9, 2018 | PLoS Neglected Tropical Diseases

Yadunanda Budigi et al.

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

Yadunanda Budigi, Eugenia Z Ong, Luke N Robinson, Li Ching Ong, Kirk J Rowley, Alexander Winnett, Hwee Cheng Tan, Sven Hobbie, Zachary Shriver, Gregory J Babcock, Sylvie Alonso, Eng Eong Ooi

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Featured publications

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Multi-omic single cell sequencing: Overview and opportunities for kidney disease therapeutic development

Quantifying the nativeness of antibody sequences using long short-term memory networks

Quantifying the nativeness of antibody sequences using long short-term memory networks

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy

Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data

Structural prediction of antibody-APRIL complexes by computational docking constrained by antigen saturation mutagenesis library data

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

Antibody-Bactericidal Macrocyclic Peptide Conjugates to Target Gram Negative Bacteria

Antibody-Bactericidal Macrocyclic Peptide Conjugates to Target Gram Negative Bacteria

Extending human IgG half-life using structure-guided design.

Extending human IgG half-life using structure-guided design.

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

Preclinical evaluation of VIS513, a therapeutic antibody against dengue virus, in non-human primates.

Preclinical evaluation of VIS513, a therapeutic antibody against dengue virus, in non-human primates.

A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.

A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.