Steven Holtzman joined Decibel Therapeutics as President and Chief Executive Officer in 2016. Decibel discovers and develops novel therapeutic approaches to treat hearing loss and other hearing disorders.
Prior to Decibel, he served as Executive Vice President, Corporate Development at Biogen, Inc. At Biogen, Mr. Holtzman created and led the program leadership and management group through six new drug approvals. He also led the business development and M&A group through successful completion of numerous transactions.
Prior to Biogen, Mr. Holtzman served as the Founder, Chief Executive Officer and Chair of the Board of Directors of Infinity Pharmaceuticals, Inc., a cancer drug discovery and development company. He was also an early leader and the Chief Business Officer of Millennium Pharmaceuticals (now Takeda Oncology), a pioneer in largescale genetics and genomics, and was a Founder, member of the board and the Executive Vice President of DNX Corporation, the first transgenic animal company. Mr. Holtzman is a member of the boards of directors of PMV Pharma, Visterra, Humatics, The Sync Project and Molecular Partners. In the not-for-profit arena, Mr. Holtzman is currently a trustee of the Berklee College of Music and previously served as the Vice Chairman of the Board of Trustees of the Hastings Center for Ethics and the Life Sciences. From 1996 to 2001, he served as a Presidential appointee to the U.S. National Bioethics Advisory Commission.
Mr. Holtzman received his B.A. in philosophy from Michigan State University and his B.Phil. graduate degree in philosophy from Corpus Christi College, Oxford University, which he attended as a Rhodes Scholar.
Previously, Dr. Halse was a partner with the corporate venture capital arm of Partners HealthCare, a large academic medical center and Harvard Medical School affiliate, based in Boston, US. In this role, he led investments and had Board responsibility for a number of therapeutics and technology platform companies, spanning infectious disease, oncology, neurology, inflammation and genome editing. Prior to this, he was a founding member of a US-based product development company, BioMed Valley Discoveries, that in-licensed and advanced a number of oncology assets into clinical trials. He also had management roles of increasing responsibility at Novartis, based in the US, initially in the diabetes and metabolism group, and then in an internal incubator with a mandate to develop programs outside the core disease areas. Earlier in his career, he led research at Xcellsyz Ltd, a venture-backed start up in the UK. Dr. Halse holds a B.Sc. and Ph.D. from Newcastle University, UK.